Institute of Neurological Recovery Blog

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Randomized, placebo-controlled, double-blind clinical trial confirms the efficacy of perispinal etanercept

Perispinal Etanercept RCT 2019

Gold Coast, Australia (January 3, 2020): The results of a randomized, placebo-controlled, double-blind clinical  trial of perispinal etanercept were published today, confirming the efficacy and remarkable results of perispinal etanercept in a cohort of stroke survivors with relentless, intractable daily pain after stroke. The individuals were treated an average of about 4 years after stroke and each reported constant daily pain after their stroke that had failed to adequately respond to all previous forms of treatment. They received two doses of perispinal etanercept, each two weeks apart, with the control group receiving two doses of saline administered perispinally. The control group had no change in their daily pain, but the etanercept group had a significant reduction in pain, measured at 30 days, with 30% of the etanercept patients showing near complete pain abatement after the first etanercept treatment. The study concludes: “Perispinal etanercept can provide significant and ongoing benefits for the chronic post-stroke management of pain and greater shoulder flexion by the paretic arm. Effects are rapid and highly significant, supporting direct action on brain function.”

The clinical trial results published on January 3, 2020 in the journal  Expert Opinion on Investigational Drugs. Learn More.

 

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Stroke Breakthrough – Multiple improvements after treatment by Edward Tobinick, M.D., on 12/26/19

Patient from Cali, Columbia able to salsa within minutes after perispinal etanercept treatment by Dr. Tobinick. Multiple additional neurological improvements occurred, including reductions in chronic post-stroke pain and neglect; and improvements in hand and arm control, balance, and agility and reduced right eyelid droop (ptosis). Filmed at the Institute of Neurological Recovery (INR®) in Boca Raton, Florida, December 26, 2019.

Text, images and video © 2019, INR PLLC, all rights reserved.

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Disclaimer: Individual results vary, not all patients respond. Additional doses may be necessary to maintain the clinical response. Treatment is innovative (“off-label”). Terms of Use

 

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Able to walk unassisted after treatment by Edward Tobinick, M.D. on 12/4/19

Family from Columbia. Able to walk unassisted immediately after treatment with perispinal etanercept by Dr. Tobinick. Filmed at the Institute of Neurological Recovery in Boca Raton, Florida, December 4, 2019.

Text, images and video © 2019, INR PLLC, all rights reserved.

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Disclaimer: Individual results vary, not all patients respond. Additional doses may be necessary to maintain the clinical response. Treatment is innovative (“off-label”). Terms of Use

 

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Immediate neurological improvement after treatment by Edward Tobinick, M.D., two years after cardiac arrest

Perispinal etanercept treatment by Dr. Tobinick at the Institute of Neurological Recovery in Boca Raton, Florida, November 15, 2019.

Text, images and video © 2019, INR PLLC, all rights reserved.

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Disclaimer: Individual results vary, not all patients respond. Additional doses may be necessary to maintain the clinical response. Treatment is innovative (“off-label”). Terms of Use

 

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Rapid improvements 3 years post-stroke after treatment by Edward Tobinick, M.D.

Perispinal etanercept treatment by Dr. Tobinick at the INR in Boca Raton, Florida, on October 25, 2019.

Text, images and video © 2019, INR PLLC, all rights reserved.

Request a consultation today

Disclaimer: Individual results vary, not all patients respond. Additional doses may be necessary to maintain the clinical response. Treatment is innovative (“off-label”). Terms of Use