Excess cerebral TNF causing glutamate excitotoxicity rationalizes treatment of neurodegenerative diseases and neurogenic pain by anti-TNF agents.

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Edward Tobinick, M.D., the founder and Director of the Institute of Neurological Recovery, invented the remarkable groundbreaking perispinal etanercept treatment for stroke and chronic brain injury in 2010. Now, in 2024, there have been thousands of individuals with chronic stroke symptoms successfully treated by Dr. Tobinick. Dr. Tobinick has now treated individuals from every state in the U.S. and from 102 countries.

In October 2018, the Australian Government announced their designation of substantial funding to study perispinal etanercept(PSE) for treatment of stroke. On January 3, 2020 a university, double-blind, randomized, placebo-controlled, clinical trial confirmed the efficacy of perispinal etanercept for treatment of chronic neurological symptoms after stroke. Dr. Tobinick was instrumental in the design of the university study.

Dr. Tobinick accepts patients for treatment from all parts of the world, and has treated patients from every populated continent of the world.

Scientific articles from hundreds of academic scientists around the world have cited Dr. Tobinick's scientific publications.

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